White Matter Hyperintensities In Young Adults

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Tuesday, July 18, 2023
The overall prevalence of WMH was 25.
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In this preliminary study involving young adults without clinical evidence of cerebrovascular disease, a greater number of modifiable cardiovascular risk factors at recommended levels was associated with higher cerebral vessel density and caliber, higher cerebral blood flow, and fewer white matter hyperintensities.
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"White matter hyperintensities" (lesions that appear bright white on certain sequences of MRI scans) " Leukoaraiosis " (a term that is used if the spots are thought to be caused by decreased blood flow. 05), but the prevalence of WMH was higher among older patients ( p < 0.
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Methods: MRI scans were conducted at baseline in HR individuals (n = 131), patients with BD .
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5 years . There was no significant difference in the prevalence of WMH by sex ( p > 0.
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Conclusions and Relevance In this preliminary study involving young adults without clinical evidence of cerebrovascular disease, a greater number of modifiable cardiovascular risk factors at recommended levels was associated with higher cerebral vessel density and caliber, higher cerebral blood flow, and fewer white matter hyperintensities . White matter hyperintensities in mid-adult life. org . May 7, 2019 · WMH is frequently found in young clinical patients.
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White Matter Disease



In this study, we used functional magnetic resonance imaging to characterize the patterns of brain activation during a working memory task in older participants with high and low levels of education (as a proxy of CR) and high and low WMH volumes. A recent study in young adults reported that large-artery atherosclerosis was more frequent in . Older age and CVD are risk factors for WMH.
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These areas may indicate some type of injury to the brain, perhaps due to decreased blood flow in that area. Hypertension among young people is common, affecting 1 in 8 adults aged between 20 and 40 years.
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The purpose of this study was to investigate the prevalence of white matter hyperintensity (WMH) without specific causes in young clinical outpatients.
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Prior studies have been constrained by small sample sizes and/or poor age- and sex-matching of …. coined the term leuko-araiosis (white matter rarefaction) to describe and define it. New imaging techniques present an opportunity to examine white matter pathology in great detail in younger populations. White matter diseases include a wide spectrum of disorders that have in common impairment of normal myelination, either by secondary destruction of previously myelinated structures (demyelinating processes) or by primary abnormalities of myelin formation (dysmyelinating processes).

⚕️ Making Sense of White Matter Disease by James G. Smirniotopoulos, M.D.




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Mar 15, 2023 · Abstract (1) Background: to investigate the prevalence of white matter hyperintensities (WMH), risk factors, and correlation with enlarged perivascular spaces (ePVS) among young patients (age, 16–45 years) in a neurological outpatient clinic. With the wide use of brain MRI, white matter hyperintensity (WMH) is frequently observed in clinical patients. White matter hyperintensities are common in MRIs of asymptomatic individuals, and their prevalence increases with age from approximately 10% to 20% in those approximately 60 years old to close to 100% in those older than 90 years.
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